化工进展 ›› 2012, Vol. 31 ›› Issue (01 ): 169-175.

• 生物化工 • 上一篇    下一篇

非水相中酶法合成糖酯的研究进展

郭艳霞1,胡  燚1,王  莹2,江  凌1,邹  彬1,宋  萍1   

  1. 1南京工业大学生物与制药工程学院,江苏 南京 210009,2中国生物技术发展中心,北京 100039
  • 出版日期:2012-01-05 发布日期:2012-01-05

Research advances in enzyme-catalytic synthesis of sugar ester in non-aqueous phase

GUO Yanxia1,HU Yi1,WANG Ying2,JIANG Ling1,ZOU Bin1,SONG Ping1   

  1. (1College of Biotechnology and Pharmaceutical Engineering ,Nanjing University of Technology,Nanjing 210009, Jiangsu,China;2 China National Center for Biotechnology Development,Beijing 100039,China)
  • Online:2012-01-05 Published:2012-01-05

摘要: 回顾了非水相酶法合成糖酯的研究进展,重点介绍了葡萄糖酯、果糖酯、蔗糖酯、麦芽糖酯和木糖醇酯的合成方法,分析了酶、溶剂、脂肪酸等对糖酯收率的影响,比较了不同糖酯酶法合成的相似性及差异性。并对其研究方向和发展前景进行了展望:酶法合成糖酯具有反应条件温和、选择性高、低毒环保等优点;采用新型反应介质、寻求既经济又环保的分离纯化方法和降低成本是研究的重点。

关键词: 脂肪酶, 糖酯, 非水相, 合成, lipase , sugar ester, non-aqueous phase , synthesis, 脂肪酶, 糖酯, 非水相, 合成

Abstract: The recent research progress of enzymatic synthesis of sugar ester is reviewed,by focusing on the methods for the synthesis of glucose ester,fructose ester, sucrose ester, maltose ester and xylitol ester. The impacts of enzyme, solvent and fatty acid on the yield of sugar ester are analyzed. The similarities and differences of enzymatic synthesis of different suger ester are compared. The outlook of enzyme-catalytic synthesis of sugar ester in the non-aqueous phase is also prospected. The enzymatic synthesis provides many advantages including mild reaction conditions,high selectivity, and low toxicity. New reaction medium, economic and environmental method of separation and purification are also emphasized.

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